Background: The factors influencing parents’ willingness to enroll their children in biobanks are poorly understood. This study sought to assess parents’ willingness to enroll their children, and their perceived benefits, concerns, and information needs under different consent and data-sharing scenarios, and to identify factors associated with willingness. Methods: This large, experimental survey of patients at the 11 eMERGE Network sites used a disproportionate stratified sampling scheme to enrich the sample with historically underrepresented groups. Participants were randomized to receive one of (...) three consent and data-sharing scenarios. Results: In total, 90,000 surveys were mailed and 13,000 individuals responded (15.8% response rate). 5737 respondents were parents of minor children. Overall, 55% (95% confidence interval 50–59%) of parents were willing to enroll their youngest minor child in a hypothetical biobank; willingness did not differ between consent and data-sharing scenarios. Lower educational attainment, higher religiosity, lower trust, worries about privacy, and attitudes about benefits, concerns, and information needs were independently associated with less willingness to allow their child to participate. Of parents who were willing to participate themselves, 25% were not willing to allow their child to participate. Being willing to participate but not willing to allow one’s child to participate was independently associated with multiple factors, including race, lower educational attainment, lower annual household income, public health care insurance, and higher religiosity. Conclusions: Fifty-five percent of parents were willing to allow their youngest minor child to participate in a hypothetical biobank. Building trust, protecting privacy, and addressing attitudes may increase enrollment and diversity in pediatric biobanks. (shrink)

Computer vision research involving street and road detection methods usually focuses on driving assistance and autonomous vehicle systems. In this context, street segmentation occurs in real-time, based on images centered on the street. This work, on the other hand, uses street segmentation for urban planning research to classify pavement types of a city or region, which is particularly important for developing countries. For this application, it is needed a dataset with images from various locations for each street. These images are (...) not necessarily centered on the street and include challenges that are not common in street segmentation datasets, such as mixed pavement types and the presence of faults and holes on the street. We implemented a multi-class version of a state-of-the-art segmentation algorithm and adapted it to perform street pavement classification, handling navigation along streets and angle variation to increase the accuracy of the classification. A data augmentation approach is also proposed to use preliminary results from the test instances as new ground truth and increase the amount of training data. A dataset with more than 300,000 images from 773 streets from a Brazilian city was built. Our approach achieved a precision of 0.93, showing the feasibility of the proposed application. (shrink)

This compact and innovative book tackles one of the central issues in drug policy: the lack of a coherent conceptual structure for thinking about drugs. Drugs generally fall into one of seven categories: prescription, over the counter, alternative medicine, common-use drugs like alcohol, tobacco and caffeine; religious-use, sports enhancement; and of course illegal street drugs like cocaine and marijuana. Our thinking and policies varies wildly from one to the other, with inconsistencies that derive more from cultural and social values than (...) from medical or scientific facts. Penalties exist for steroid use, while herbal remedies or cold medication are legal. Native Americans may legally use peyote, but others may not. Penalties may vary for using different forms of the same drug, such as crack vs. powder cocaine. Herbal remedies are unregulated by the FDA; but medical marijuana is illegal in most states. Battin and her contributors lay a foundation for a wiser drug policy by promoting consistency and coherency in the discussion of drug issues and by encouraging a unique dialogue across disciplines. The contributors are an interdisciplinary group of scholars mostly based at the University of Utah, and include a pharmacologist, a psychiatrist, a toxicologist, a trial court judge, a law professor, an attorney, a diatary specialist, a physician, a health expert on substance abuse, and Battin herself who is a philosopher. They consider questions like the historical development of current policy and the rationales for it; scientific views on how drugs actually cause harm; how to define the key notions of harm and addiction; and ways in which drug policy can be made more consistent. They conclude with an examination of the implications of a consistent policy for various disciplines and society generally. The book is written accessibly with little need for expert knowledge, and will appeal to a diverse audience of philosophers, bioethicists, clinicians, policy makers, law enforcement, legal scholars and practitioners, social workers, and general readers, as well as to students in areas like pharmacy, medicine, law, nursing, sociology, social work, psychology, and bioethics. (shrink)

Variable responses to transcranial direct current stimulation protocols across individuals are widely reported, but the reasons behind this variation are unclear. This includes tDCS protocols meant to improve attention. Attentional control is impacted by top-down and bottom-up processes, and this relationship is affected by state characteristics such as anxiety. According to Attentional Control Theory, anxiety biases attention towards bottom-up and stimulus-driven processing. The goal of this study was to explore the extent to which differences in state anxiety and related measures (...) affect visual attention and category learning, both with and without the influence of tDCS. Using discovery learning, participants were trained to classify pictures of European streets into two categories while receiving 30 min of 2.0 mA anodal, cathodal, or sham tDCS over the rVLPFC. The pictures were classifiable according to two separate rules, one stimulus and one hypothesis-driven. The Remote Associates Test, Profile of Mood States, and Attention Networks Task were used to understand the effects of individual differences at baseline on subsequent tDCS-mediated learning. Multinomial logistic regression was fit to predict rule learning based on the baseline measures, with subjects classified according to whether they used the stimulus-driven or hypothesis-driven rule to classify the pictures. The overall model showed a classification accuracy of 74.1%. The type of tDCS stimulation applied, attentional orienting score, and self-reported mood were significant predictors of different categories of rule learning. These results indicate that anxiety can influence the quality of subjects’ attention at the onset of the task and that these attentional differences can influence tDCS-mediated category learning during the rapid assessment of visual scenes. These findings have implications for understanding the complex interactions that give rise to the variability in response to tDCS. (shrink)

A SLOW revolution in cognitive science is banishing this century's technological conception of mind as disembodied pure thought, namely a material symbol manipulation, and replacing it with next century's conception: mind as the organisation of bodily interaction, intelligent robotics. Here is Clark: Intelligence and understanding are rooted not in the presence and manipulation of explicit, language-like data structures, but in something more earthy: the tuning of basic responses to a real world that enables an embodied organism to sense, act and (...) survive . . . it is now increasingly clear that the alternative to the ``disembodied explicit data manipulation'' vision of AI is not to retreat from hard science; it is to pursue some even harder science. It is to put intelligence where it belongs: in the coupling of organisms and the world that is at the root of daily, fluent action. (p. 4) # AAHPSSS, 1998. Published by Blackwell Publishers, 108 Cowley Road, Oxford OX4 1JF, and 350 Main Street, Malden MA 02148, USA.. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Material Life of Roman Slaves by Sandra R. Joshel, Lauren Hackworth PetersenJuan P. LewisSandra R. Joshel and Lauren Hackworth Petersen. The Material Life of Roman Slaves. Cambridge and New York: Cambridge University Press, 2014. xv + 286 pp. 16 color plates. Hardback, £65.00.This is an original book, even though it is does not contain new research or new findings. The title may be somewhat misleading. Rather than (...) a general study of Roman slaves’ material culture, the reader will find here an anthropology of the architecture of the spaces and built environments in which slaves dwelt and toiled (5). Thus, the focus is not so much on the material conditions in which slaves lived or the artifacts they worked with, but on the layout of a small set of first century c.e. houses, streets and economic units, mostly found in the Bay of Naples, Ostia, and the ager Cosanus. The study of space serves Joshel and Hackworth Petersen as an attempt to reconstruct slaves’ responses, through adaptation and challenge, to the choreography of movements imposed on them by their masters.Methodologically, this investigation operates on the distinction developed by Michel De Certeau (The Practice of Everyday Life [1988]) between the strategies of the powerful to delimit a space in which power relations can be managed to their own advantage and the tactics of the weak to seize the opportunities to use an imposed spatial order for their own ends (8). The authors see their work as “an act of remembrance” (222). Their aim is to make invisible slaves visible again. Slaves, they contend, have not only been silenced in classical texts written by and from the point of view of slave owners. In the process of collecting and analyzing ancient material, and in the crafting of their historic narratives, modern archaeologists, art historians, and even tourism authorities have “actively, if unwittingly made [slaves] disappear” (3). To redress the imbalance, Joshel and Hackworth Petersen walk away from mere static descriptions of archaeological sites and concentrate on the dynamic of slaves’ movements within those spaces.Although the authors rely on other archaeologists and historians’ fieldwork and interpretation of the material remains, they themselves visited most of the sites and buildings they describe. The book is profusely illustrated with sixteen plates and 170 figures, among which we find the authors’ own photographs of some of the structures they discuss, such as doorways, storage rooms, stairs, porticos, kitchens, street benches, and fountains. Other illustrations consist of maps of Pompeii, Herculaneum, and Ostia (19–21), street plans of Pompeii (plates VI, VII, and XI), and building plans of the houses, workshops and villae dealt with in the body of the text. Constant cross-reference to these images and drawings helps the reader to see and understand space in three dimensions, something [End Page 709] that it is not always easy to elicit from illustrations and archaeological reports in which findings are presented in a two-dimensional plane.The book is divided into six chapters. The Introduction (chap. 1) lays out the aims of the book and the methodological approach chosen by the authors. In the next four chapters, the discussion of built environments moves from the inside to the outside and from an urban set-up to the rural world. Chapter 2 focuses on the architectural layout of houses from Campania and Rome’s port-town, Ostia: namely, the houses of the Menander, Julius Polybius, Sutoria Primigenia, the Smith, Lucretius Fronto, the Ceii, the Vetii, and the Gilded Cupids in Pompeii; the houses of the Corinthian Atrium, the Mosaic Atrium, the Alcove, the Beautiful Courtyard, the Samnite, and the Grand Portal in Herculaneum; and the Ostian house of the Muses.The analysis of the Roman domestic landscape uses Andrew Wallace-Hadrill’s two axes of differentiation between the grand and the humble and the public and the private (Houses and Societies in Pompeii and Herculaneum [1994]:38), but the emphasis is on the slaves’ perspective within this framework, rather than the owners’—even though the latter is not absent. Particular attention is given to doorways and how they helped to choreograph movements through their diverse heights and hierarchical positions... (shrink)

An instrument to assess 'ethical sensitivity' has been developed. The instrument presents four clinical vignettes and the respondent is asked to list the ethical issues related to each vignette. The responses are classified, post hoc, into the domains of autonomy, beneficence and justice. This instrument was used in 1990 to assess the ethical sensitivity of students in all four medical classes at the University of Toronto. Ethical sensitivity, as measured by this instrument, is not related to age or grade-point average. (...) Sensitivity increases between the 1st and 2nd year and then decreases throughout the rest of undergraduate medical training, such that the 4th-year students identify fewer issues than those entering medical school. Students expressing a career choice of family medicine identify more issues than their peers. Several problems with the use of the instrument and the interpretation of the data were found. Nonetheless, these findings, if reproducible, are important and their meaning needs further discussion. (shrink)

The author is primarily concerned with the explanation of behavior in regard to (1) the mecanical model, (2) the effects of physical-organic processes on behavior, (3) the lack of understanding between philosophers and psychologists as to sufficient conditions for predicting a behavioral event, (4) conditions leading to expalantions of behavior that could predict behavior exclusive of any antecedent psychological behavior, and (5) variations of the mechanical-model introducing differing sorts of explanation. (staff).

(1982). DE GETALLENSPREUK EN ZIJN REIKWIJDTE EEN PLEIDOOI VOOR DE LITERAIRE EENHEID VAN JESUS SIRACH 26:28–27:10. Bijdragen: Vol. 43, No. 4, pp. 383-389.

Given a physical system, one knows that there is a logical duality between its properties and its states. In this paper, we choose its states as the undefined notions of our axiomatic construction. In fact, by means of well-motivated assumptions expressed in terms of a transition probability function defined on the set of all pure states of the system, we construct a system of elementary propositions, i.e., a complete orthomodular atomic lattice satisfying the covering law. We also study in this (...) framework the important notion of compatibility of propositions, and we define the superpositions and the mixtures of the states of the physical system. (shrink)

Aim To explore the views in non-Western cultures about ending the lives of damaged newborns.Method 254 university students from India and 150 from Kuwait rated the acceptability of ending the lives of newborns with genetic defects in 54 vignettes consisting of all combinations of four factors: gestational age ; severity of genetic defect ; the parents’ attitude about prolonging care ; and the procedure used .Results Four clusters were identified by cluster analysis and subjected to analysis of variance. Cluster I, (...) labelled ‘Never Acceptable’, included 4% of the Indians and 59% of the Kuwaitis. Cluster II, ‘No Firm Opinion’, had little variation in rating from one scenario to the next; it included 38% of the Indians and 18% of the Kuwaitis. In Cluster III, ‘Parents’ Attitude+Severity+Procedure’, all three factors affected the ratings; it was composed of 18% of the Indians and 16% of the Kuwaitis. Cluster IV was called ‘Severity+Parents’ Attitude’ because these had the strongest impact; it was composed of 40% of the Indians and 7% of the Kuwaitis.Conclusions In accordance with the teachings of Islam versus Hinduism, Kuwaiti students were more likely to oppose ending a newborn's life under all conditions, Indian students more likely to favour it and to judge its acceptability in light of the different circumstances. (shrink)

Reprint. Originally published: Rajini's punchtantra: value statements on business and life management. Chennai: New Horizon Media, 2010.

Originally published in 1957,the first part of this volume examines physical education in classical Greece and Imperial Rome during the first and second centuries A.D. and in Italy and England during the Renaissance. Each of these periods witnessed remarkable developments in the practice and theory of physical education: developments which still have present-day significance. The second part of the book traces the simultaneous development of physical education in different parts of the USA and Europe from the end of the eighteenth (...) century onwards. (shrink)

This book addresses the Confucian philosophy of common good and deals with the comparative philosophy on eastern and western understandings of common good. The common good is an essentially contested concept in contemporary moral and political discussions. Although the notion of the common good has a slightly antique air, especially in the North Atlantic discussion, it has figured prominently in both the sophisticated theoretical accounts of moral and political theory in recent years and also in the popular arguments brought for (...) particular political policies and for more general orientations toward policy. It has been at home both in the political arsenal of the left and the right and has had special significance in ethical and political debates in modern and modernizing cultures. This text will be of interest to philosophers interested in Chinese philosophy and issues related to individualism and communitarianism, ethicists and political philosophers, comparative philosophers, and those in religious studies working on Chinese religion. (shrink)

The study of the interrelationship between ethnomedicinal knowledge and socio-cultural values needs to be studied mainly for the simple reason that culture is not only the ethical imperative for development, it is also the condition of its sustainability; for their exists a symbiotic relationship between habitats and cultures. The traditional communities around Binsar Wildlife Sanctuary of Uttarakhand state in India have a rich local health care tradition, which has been in practice for the past hundreds of years. The present study (...) documents the Ethnomedicinal uses of 54 medicinal and aromatic plants (MAPs) along with their botanical and vernacular names, family, habit, habitat, threat status, collection season, purpose of collection, quantity, conservation practices, market potential and part(s) used in traditional health care system. The documented species belonging to 38 families have been used to cure more than 47 different kinds of ailments. These MAPs collected from the wild in a particular season and used as per the method prescribed by traditional herbal healers (Vaidyas) that provide effective results. Perception of local people during field trips based on socio-demographic characters showed them to prefer herbal system of treatments and they understood the status of traditional health care systems in the region. The study reveals that approximately 70 % population of the study area depend on herbal systems of treatments and preferred to visit Vaidyas for curing a variety of ailments because the traditional system of medicine is one of the most important prevailing systems in the region where modern health care facilities are rare or in very poor conditions. The organic cultivation practices of selected MAPs were demonstrated to rural inhabitants through capacity building training program and participatory action research framework approaches for sustainability and enhancement of livelihood security. A series of workshops and village level meetings on traditional health care systems were organized and forming/registered a strong association of Vaidyas for making their traditional system of health care more practical and effective. The study emphasizes the potentials of the ethnomedicinal research, conservation practices, socio-cultural and religious ethics for promoting traditional plants based treatments and also the need to document the indigenous knowledge for scientific validation before its industrial application. (shrink)

There have been many claims that quantum mechanics plays a key role in the origin and/or operation of biological organisms, beyond merely providing the basis for the shapes and sizes of biological molecules and their chemical affinities. These range from Schr¨odinger’s suggestion that quantum fluctuations produce mutations, to Hameroff and Penrose’s conjecture that quantum coherence in microtubules is linked to consciousness. I review some of these claims in this paper, and discuss the serious problem of decoherence. I advance some further (...) conjectures about quantum information processing in bio-systems. Some possible experiments are suggested. © 2004 Elsevier Ireland Ltd. All rights reserved. (shrink)